{predictNMB}

Rex Parsons

The next hour of your life

  • Who am I?
  • Who are you?
  • What is a clinical decision support system?
  • THE ENTIRE FIELD OF HEALTH ECONOMICS
  • coding with {predictNMB}

Who am I?

Who am I?

Who am I?

Who am I?

Who am I?

Who am I?

Who am I?

Currently:

PhD Candidate and Senior Research Assistant at AusHSI (QUT)

Previously:

Work

  • Data Analyst - IVF (City Fertility)
  • Research Assistant - Radiology (IMED)
  • Scientist - Medical Diagnostics (Ellume)

School

  • BSc Physiotherapy (DNF)
  • BSc Biomedical Science
  • Honours (Neuroscience)
  • Master of Medical Statistics


2019-2020

2018-2019

2016-2018



2012-2014

2015-2016

2017

2019-2020

Who are you?

What is a clinical Decision Support System?

What is a clinical Decision Support System?

annalise.ai’s chest x-ray decision support

  • Assesses chest x-ray for 124 possible outcomes
  • Ranks outcomes and communicates risk to user
  • Highlights areas of image that are influential to risk estimate
  • clinical prediction model
  • reduces/prioritises information
  • model interpretation for better decision (?)

What is a clinical prediction model?

Diagnostic

What is a clinical prediction model?

Prognostic

What is a clinical prediction model?

Prognostic

THE ENTIRE FIELD OF HEALTH ECONOMICS

THE ENTIRE FIELD OF HEALTH ECONOMICS

What you need to know…

  • Healthcare systems are resource constrained
  • Health economics concerns how best to allocate resources
  • Some terms…

Quality-adjusted life years (QALYS)

Generic measure of disease burden that considers quality and duration of life

Willingness-to-pay (WTP)

“The maximum price at or below a customer would pay for a product”

AKA

“The price at which a healthcare payer is willing to pay for an additional quality-adjust life year”

Incremental cost-effectiveness ratio (ICER)

\[ICER = \frac{Cost_{A}-Cost_{B}}{QALY_{A}-QALY_{B}}\]

ICER = Cost per additional QALY gained

if (ICER < WTP) {
  print("Treatment is cost-effective!")
}

Cost-effectiveness

Cost-effectiveness plot

Cost-effectiveness plot

Cost-effectiveness plot

Cost-effectiveness plot

Cost-effectiveness plot

Cost-effectiveness plot

Cost-effectiveness plot

Cost-effectiveness plot

Cost-effectiveness plot

(Incremental) Net Monetary Benefit

NMB: Summary of benefit in monetary terms

\[NMB = QALY \times WTP - Cost_{treatment}\] INB: Difference in NMB between two strategies

\[INB_{A} = NMB_{A} - NMB_{ref}\]

{predictNMB}

{predictNMB}

What is the expected health economic benefit of using a given (hypothetical) CDSS?

docs.ropensci.org/predictNMB/

install.packages("predictNMB")